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EPTN International Neurological Contouring Atlas (INCA) instruction videos

David Hofstede, Dario Di Perri, Erik Roelofs, Alida Postma, Esther Troost, Daniëlle Eekers

Ten new organs at risk (OAR) were recently introduced in the update of the EPTN neurological contouring atlas (Eekers, 2021, doi:10.17195/candat.2021.02.1): amygdala, caudate nucleus, corpus callosum, fornix, macula, optic tract, orbitofrontal cortex, periventricular space, pineal gland, and thalamus. These are thought to be associated with cognition, vision, or radiological changes after irradiation of the brain. Accurate delineation of these OARs on a large scale is essential to gather dosimetric data usable as input for normal tissue complication probability models.

In this context, educational movies were developed in order to facilitate the contouring of these OARs and to reduce inter- and intra-individual delineation variability. The movies are designed to be used by all the professionals involved in contouring. Each movie describes the anatomical limits of one of the ten new OARs and provides tips & tricks to help with common difficulties faced during delineation.

Please site this set of instructions as follows:

Hofstede D, Di Perri D, Roelofs E, Postma A, Troost EG, Eekers DBP
EPTN International Neurological Contouring Atlas (INCA) instruction videos
CancerData, 2022; doi:10.17195/candat.2022.02.1

EPTN consensus-based toxicity scoring standard for the follow-up of adult brain and base of skull tumours after radiotherapy

Laurien De Roeck, Hiska L van der Weide, Daniëlle BP Eekers, Erik Roelofs, Esther GC Troost, Maarten Lambrecht

De Roeck et al. have published a guideline for consistent toxicity scoring and follow-up in adult brain tumour patients in consensus with the European Particle Therapy Network (EPTN). The purpose of this framework is to enable the collection of uniform toxicity data of brain tumour patients treated with photon and particle therapy. This will facilitate collaboration and further propel the research field of radiation-induced toxicities relevant for these patients.

Please site this table as follows:

Laurien De Roeck, Hiska L van der Weide, Daniëlle BP Eekers, Erik Roelofs, Esther GC Troost, Maarten Lambrecht
EPTN consensus-based toxicity scoring standard for the follow-up of adult brain and base of skull tumours after radiotherapy
CancerData, 2021; doi:10.17195/candat.2021.09.1

Benefit of particle therapy in re-irradiation of head and neck patients. Results of a multicentric in silico ROCOCO trial

Daniëlle B.P. Eekers, Erik Roelofs, Urszula Jelen, Maura Kirk, Marlies Granzier, Filippo Ammazzalorso, Peter H. Ahn, Geert O.R.J Janssens, Frank J.P. Hoebers, Tobias Friedmann, Timothy Solberg, Sean Walsh, Esther G.C. Troost, Johannes H.A.M. Kaanders, Philippe Lambin

Background and Purpose

In this multicentric in silico trial we compared photon, proton, and carbon ion radiotherapy plans for re-irradiation of patients with squamous cell carcinoma of the head and neck (HNSCC) regarding dose to tumour and doses to surrounding organs at risk (OARs).

Material and Methods