Sharing data for cancer research
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Below, an overview of all published information is given. Use the tabs to navigate between types of information.Title | Authors | Year | DOI |
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EPTN International Neurological Contouring Atlas (INCA) instruction videos | David Hofstede, Dario Di Perri, Erik Roelofs, Alida Postma, Esther Troost, Daniëlle Eekers | 2022 | 10.17195/candat.2022.02.1 |
EPTN consensus-based toxicity scoring standard for the follow-up of adult brain and base of skull tumours after radiotherapy | Laurien De Roeck, Hiska L van der Weide, Daniëlle BP Eekers, Erik Roelofs, Esther GC Troost, Maarten Lambrecht | 2021 | 10.17195/candat.2021.09.1 |
EPTN International Neurological Contouring Atlas - 2021 Update | Daniëlle Eekers, Dario Di Perri, Erik Roelofs, Alida Postma, Esther Troost | 2021 | 10.17195/candat.2021.02.1 |
EPTN consensus-based guideline for the tolerance dose per fraction of organs at risk in the brain | Daniëlle BP Eekers, Maarten Lambrecht, Petra De Witt Nyström, Ans Swinnen, Frederik WR Wesseling, Erik Roelofs, Esther GC Troost | 2018 | 10.17195/candat.2018.01.1 |
Optimization of Brain and Head & Neck Radiotherapy | Daniëlle BP Eekers | 2018 | 10.17195/candat.2018.12.7 |
Atlas for the delineation for organs-at-risk in NSCLC | Heike Peulen, José Belderbos, Matthias Guckenberger, Andrew Hope, Inga Grills, Marcel van Herk, Jan-Jakob Sonke | 2017 | 10.17195/candat.2017.04.1 |
EPTN International Neurological Contouring Atlas | Daniëlle Eekers, Lieke In T Ven, Erik Roelofs, Alida Postma, Esther G Troost | 2017 | 10.17195/candat.2017.08.1 |
Developing and validating a survival prediction model for NSCLC patients through distributed learning across three countries | Arthur Jochems, Timo M. Deist, Issam El Naqa, Marc Kessler, Chuck Mayo, Jackson Reeves, Shruti Jolly, Martha Matuszak, Randall Ten Haken, Johan van Soest, Cary Oberije, Corinne Faivre-Finn, Gareth Price, Dirk de Ruysscher, Philippe Lambin, Andre Dekker | 2017 | 10.1016/j.ijrobp.2017.04.021 |
ULISSE: Umbrella protocoL ISSue for oncological patiEnts | Vincenzo Valentini | 2017 | 10.17195/candat.2016.09.1 |
Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer – Comparison of dose, toxicity and cost-effectiveness | Qing Cheng, Erik Roelofs, Bram L.T. Ramaekers, Daniëlle Eekers, Johan van Soest, Tim Lustberg, Tim Hendriks, Frank Hoebers, Hans Paul van der Laan, Erik W. Korevaar, Andre Dekker, Johannes A. Langendijk, Philippe Lambin | 2016 | 10.1016/j.radonc.2015.12.029 |
From Data to Decision - A Knowledge Engineering approach to individualise cancer therapy | Erik Roelofs | 2016 | 10.17195/candat.2016.07.1 |
Advanced MR Imaging Protocol for Glioblastoma | Yue Cao | 2016 | 10.17195/candat.2016.03.1 |
Prognostic value of blood-biomarkers related to hypoxia, inflammation, immune response and tumour load in non-small cell lung cancer - a survival model with external validation | Sara Carvalho, Esther G.C. Troost, Judith Bons, Paul Menheere, Philippe Lambin, Cary Oberije | 2016 | 10.1016/j.radonc.2016.04.024 |
Benefit of particle therapy in re-irradiation of head and neck patients. Results of a multicentric in silico ROCOCO trial | Daniëlle B.P. Eekers, Erik Roelofs, Urszula Jelen, Maura Kirk, Marlies Granzier, Filippo Ammazzalorso, Peter H. Ahn, Geert O.R.J Janssens, Frank J.P. Hoebers, Tobias Friedmann, Timothy Solberg, Sean Walsh, Esther G.C. Troost, Johannes H.A.M. Kaanders, Philippe Lambin | 2016 | 10.1016/j.radonc.2016.08.020 |
PET-based dose painting in non-small cell lung cancer: Comparing uniform dose escalation with boosting hypoxic and metabolically active sub-volumes | Aniek J.G. Even, Judith van der Stoep, Catharina M.L. Zegers, Bart Reymen, Esther G.C. Troost, Philippe Lambin, Wouter van Elmpt | 2015 | 10.1016/j.radonc.2015.07.013 |
Multi-state statistical modeling: a tool to build a lung cancer micro-simulation model that includes parameter uncertainty and patient heterogeneity | M.L. Bongers, D. De Ruysscher, C. Oberije, P.Lambin, C.A. Uyl-de Groot, V.M.H. Coupé | 2015 | 10.1177/0272989X15574500 |
A validated prediction model for overall survival from Stage III Non Small Cell Lung Cancer: towards survival prediction for individual patients. | Cary Oberije, Dirk De Ruysscher, Ruud Houben, Michel van de Heuvel, Wilma Uyterlinde, Joseph Deasy, Jose Belderbos, Anne-Marie C. Dingemans, Andreas Rimner, Shaun Din, Philippe Lambin | 2015 | 10.1016/j.ijrobp.2015.02.048 |
Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach | Hugo J. W. L. Aerts, Emmanuel Rios Velazquez, Ralph T. H. Leijenaar, Chintan Parmar, Patrick Grossmann, Sara Carvalho, Johan Bussink, René Monshouwer, Benjamin Haibe-Kains, Derek Rietveld, Frank Hoebers, Michelle M. Rietbergen, C. René Leemans, Andre Dekker, John Quackenbush, Robert J. Gillies, Philippe Lambin | 2014 | 10.1038/ncomms5006 |
Externally validated HPV-based prognostic nomogram for oropharyngeal carcinoma patients yields more accurate predictions than TNM staging | Emmanuel Rios Velazquez, Frank Hoebers, Hugo J.W.L. Aerts, Michelle M. Rietbergen, Ruud H. Brakenhoff, C. René Leemans, Ernst-Jan Speel, Jos Straetmans, Bernd Kremer, Philippe Lambin | 2014 | 10.1016/j.radonc.2014.09.005 |
EuroCAT Umbrella Protocol for NSCLC | Cary Oberije, Esther Troost, Michael Eble, Paul Bulens, Philippe Coucke, Katrien De Jaeger, Philippe Lambin | 2013 | 10.17195/candat.2013.08.1 |
International data-sharing for radiotherapy research: an open-source based infrastructure for multicentric clinical data mining | Erik Roelofs, André Dekker, Elisa Meldolesi, Ruud G.P.M. van Stiphout, Vincenzo Valentini, Philippe Lambin | 2013 | 10.1016/j.radonc.2013.11.001 |
Prognostic value of metabolic metrics extracted from baseline positron emission tomography images in non-small cell lung cancer | Carvalho S, Leijenaar RT, Velazquez ER, Oberije C, Parmar C, van Elmpt W, Reymen B, Troost EG, Oellers M, Dekker A, Gillies R, Aerts HJ, Lambin P | 2013 | 10.3109/0284186X.2013.812795 |
Cardiac comorbidity is an independent risk factor for radiation-induced lung toxicity in lung cancer patients | Georgi Nalbantov, Bas Kietselaer, Katrien Vandecasteele, Cary Oberije, Maaike Berbee, Esther Troost, Anne-Marie Dingemans, Angela van Baardwijk, Kim Smits, André Dekker, Johan Bussink, Dirk De Ruysscher, Yolande Lievens, Philippe Lambin | 2013 | 10.1016/j.radonc.2013.08.035 |
A semiautomatic CT-based ensemble segmentation of lung tumors: Comparison with oncologists’ delineations and with the surgical specimen | Emmanuel Rios Velazquez, Hugo J.W.L. Aerts, Yuhua Gu, Dmitry B. Goldgof, Dirk De Ruysscher, Andre Dekker, René Korn, Robert J. Gillies, Philippe Lambin | 2012 | 10.1016/j.radonc.2012.09.023 |
Standard Follow Up Program For Head And Neck Cancer Patients | Johannes A. Langendijk, Phillipe Lambin | 2012 | 10.17195/candat.2012.01.1 |
The prognostic value of temporal in vitro and in vivo derived hypoxia gene-expression signatures in breast cancer | Maud H.W. Starmans, Kenneth C. Chu, Syed Haider, Francis Nguyen, Renaud Seigneuric, Michael G. Magagnin, Marianne Koritzinsky, Arek Kasprzyk, Paul C. Boutros, Bradly G. Wouters, Philippe Lambin | 2012 | 10.1016/j.radonc.2012.02.002 |
Preclinical evaluation and validation of [18F]HX4, a promising hypoxia marker for PET imaging | Ludwig J. Dubois, Natasja G. Lieuwes, Marco H. M. Janssen, Wenny J. M. Peeters, Albert D. Windhorst, Joseph C. Walsh, Hartmuth C. Kolb, Michel C. Öllers, Johan Bussink, Guus A. M. S. van Dongen, Albert van der Kogel, Philippe Lambin | 2011 | 10.1073/pnas.1102526108 |
PET imaging of hypoxia using [18F]HX4: a phase I trial | Judith van Loon, Marco H. M. Janssen, Michel Öllers, Hugo J. W. L. Aerts, Ludwig Dubois, Monique Hochstenbag, Anne-Marie C. Dingemans, Roy Lalisang, Boudewijn Brans, Bert Windhorst, Guus A. van Dongen, Hartmuth Kolb, James Zhang, Dirk De Ruysscher, Philippe Lambin | 2010 | 10.1007/s00259-010-1437-x |
Data from: Prognostic value of blood-biomarkers related to hypoxia, inflammation, immune response and tumour load in non-small cell lung cancer – a survival model with external validation | S. Carvalho; E.G.C. Troost; J. Bons; P. Menheere; P. Lambin; C. Oberije | 2016 | 10.17195/candat.2016.04.1 |
Radiomics Digital Phantom | P. Lambin | 2016 | 10.17195/candat.2016.08.1 |
Data from: 4DCT imaging to assess radiomics feature stability: an investigation for thoracic cancers | R.T.H.M. Larue; L. Van De Voorde; J.E. van Timmeren; R.T.H. Leijenaar; M. Berbee; M.N. Sosef; W.M.J. Schreurs; W. van Elmpt; P. Lambin | 2017 | 10.17195/candat.2017.05.1 |
Preclinical evaluation and validation of [18F]HX4, a promising hypoxia marker for PET imaging | L.J. Dubois; N.G. Lieuwes; M.H.M. Janssen; W.J.M. Peeters; A.D. Windhorst; J.C. Walsh; H.C. Kolb; M.C. Oellers; J. Bussink; G.A.M.S. van Dongen; A. van der Kogel; P. Lambin | 2011 | 10.1073/pnas.1102526108 |
Externally validated HPV-based prognostic nomogram for oropharyngeal carcinoma patients yields more accurate predictions than TNM staging. | E.Rios Velazquez; F. Hoebers; H.J.W.L. Aerts; M.M. Rietbergen; R.H. Brakenhoff; R.C. Leemans; E.J. Speel; J. Straetmans; B. Kremer; P. Lambin | 2014 | 10.1016/j.radonc.2014.09.005 |
A Validated Prediction Model for Overall Survival From Stage III Non-Small Cell Lung Cancer: Toward Survival Prediction for Individual Patients. | C. Oberije; D. De Ruysscher; R. Houben; M. van de Heuvel; W. Uyterlinde; J.O. Deasy; J. Belderbos; A.M.C. Dingemans; A. Rimner; S. Din; P. Lambin | 2015 | 10.1016/j.ijrobp.2015.02.048 |
Data from: Benefit of particle therapy in re-irradiation of head and neck patients. Results of a multicenter in silico ROCOCO trial | D. Eekers; E. Roelofs; U. Jelen; M. Kirk; M. Granzier; F. Ammazzalorso; P.H. Ahn; G.O.R.J. Janssens; F. Hoebers; T. Friedmann; T. Solberg; S. Walsh; E.G.C. Troost; J.H.A.M. Kaanders; P. Lambin | 2016 | 10.17195/candat.2016.04.2 |
Data from: Quantitative assessment of Zirconium-89 labeled cetuximab using PETCT imaging in patients with advanced head and neck cancer - a theragnostic approach | A. Even; O. Hamming-Vrieze; W. van Elmpt; V. Winnepenninckx; J. Heukelom; M. Tesselaar; W. Vogel; A. Hoeben; C.M.L. Zegers; D. Vugts; G. Van Dongen; H. Bartelink; F. Mottaghy; F. Hoebers; P. Lambin | 2016 | 10.17195/candat.2016.11.1 |
The posterior cerebellum, a new organ at risk? | D.B.P. Eekers; Lin 't Ven; S. Deprez; L. Jacobi; E. Roelofs; A. Hoeben; P. Lambin; D. De Ruysscher; E.G.C. Troost | 2018 | 10.1016/j.ctro.2017.11.010 |
Benefits of a clinical data warehouse with data mining tools to collect data for a radiotherapy trial | E. Roelofs; L. Persoon; S. Nijsten; W. Wiessler; A. Dekker; P. Lambin | 2013 | 10.1016/j.radonc.2012.09.019 |
PET imaging of hypoxia using [18F]HX4: a phase I trial | J. Loon; M.H.M. Janssen; M.C. Oellers; H.J.W.L. Aerts; L.J. Dubois; M. Hochstenbag; A.M.C. Dingemans; R. Lalisang; B. Brans; B. Windhorst; G.A. Dongen; H.C. Kolb; J. Zhang; D. De Ruysscher; P. Lambin | 2010 | 10.1007/s00259-010-1437-x |
Prognostic value of metabolic metrics extracted from baseline positron emission tomography images in non-small cell lung cancer. | S. Carvalho; R.T.H. Leijenaar; E.Rios Velazquez; C. Oberije; C. Parmar; W. van Elmpt; B. Reymen; E.G.C. Troost; M. Oellers; A. Dekker; R. Gillies; H.J.W.L. Aerts; P. Lambin | 2013 | 10.3109/0284186X.2013.812795 |
Data from: Development and Evaluation of an Online Three-Level Proton vs Photon Decision Support Prototype for Head and Neck Cancer - Comparison of Dose, Toxicity and Cost-Effectiveness | Q. Cheng; E. Roelofs; B. Ramaekers; D. Eekers; J. van Soest; T. Lustberg; F. Hoebers; H.Paul van der Laan; E. Korevaar; A. Dekker; J. Langendijk; P. Lambin | 2015 | 10.17195/candat.2015.10.5 |
From Data to Decision - A Knowledge Engineering approach to individualise cancer therapy | E. Roelofs | 2016 | 10.17195/candat.2016.07.01 |
Data from: Survival prediction of non-small cell lung cancer patients using radiomics analyses of cone-beam CT images | J. van Timmeren; R.T.H. Leijenaar; W. van Elmpt; B. Reymen; C. Oberije; R. Monshouwer; J. Bussink; C. Brink; O. Hansen; P. Lambin | 2017 | 10.17195/candat.2017.02.1 |
Data from: Intensity-modulated proton therapy decreases dose to organs at risk in low-grade glioma patients: results of a multicentric in silico ROCOCO trial | D. Eekers; E. Roelofs; M. Cubillos-Mesias; C. Niël; R.Jan Smeenk; A. Hoeben; A.W.H. Minken; J.H.A.M. Kaanders; P. Lambin; E.G.C. Troost | 2018 | 10.17195/candat.2018.05.1 |
Cardiac comorbidity is an independent risk factor for radiation-induced lung toxicity in lung cancer patients | G. Nalbantov; B. Kietselaer; K. Vandecasteele; C. Oberije; M. Berbee; E.G.C. Troost; A.M.C. Dingemans; A. van Baardwijk; K. Smits; A. Dekker; J. Bussink; D. De Ruysscher; Y. Lievens; P. Lambin | 2013 | 10.1016/j.radonc.2013.08.035 |
International data-sharing for radiotherapy research: an open-source based infrastructure for multicentric clinical data mining. | E. Roelofs; A. Dekker; E. Meldolesi; R.G.P.M. van Stiphout; V. Valentini; P. Lambin | 2014 | 10.1016/j.radonc.2013.11.001 |
A semiautomatic CT-based ensemble segmentation of lung tumors: comparison with oncologists' delineations and with the surgical specimen. | E.Rios Velazquez; H.J.W.L. Aerts; Y. Gu; D.B. Goldgof; D. De Ruysscher; A. Dekker; R. Korn; R.J. Gillies; P. Lambin | 2012 | 10.1016/j.radonc.2012.09.023 |
Data from: MMP2 small immuno protein antibody uptake in xenograft tumors is associated with MMP2 activity | K. Panth; T. van den Beucken; R. Biemans; N. Lieuwes; M. Weber; M. Losen; A. Yaromina; L. Dubois; P. Lambin | 2015 | 10.17195/candat.2015.10.6 |
Data from: Nitroglycerin in non-small cell lung cancer: does it impact tumor hypoxia and tumor perfusion? A window-of-opportunity clinical trial. | B. Reymen; M.W. van Gisbergen; A.J.G. Even; C.M.L. Zegers; C. Oberije; F. Mottaghy; M. Das; A. Yaromina; W. van Elmpt; D. De Ruysscher; L. Dubois; P. Lambin | 2016 | 10.17195/candat.2016.07.2 |
Data from: Developing and validating a survival prediction model for NSCLC patients through distributed learning across three countries | A. Jochems; T.M. Deist; I.El Naqa; M. Kessler; C. Mayo; J. Reeves; S. Jolly; M. Matuszak; R.Ten Haken; J. van Soest; C. Oberije; C. Faivre-Finn; G. Price; D. De Ruysscher; P. Lambin; A. Dekker | 2017 | 10.17195/candat.2017.02.2 |
Optimization of Brain and Head & Neck Radiotherapy | D.B.P. Eekers | 2018 | 10.17195/candat.2018.12.7 |
The prognostic value of temporal in vitro and in vivo derived hypoxia gene-expression signatures in breast cancer | M.H.W. Starmans; K.C. Chu; S. Haider; F. Nguyen; R. Seigneuric; M.G. Magagnin; M. Koritzinsky; A. Kasprzyk; P.C. Boutros; B.G. Wouters; P. Lambin | 2012 | 10.1016/j.radonc.2012.02.002 |
Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach. | H.J.W.L. Aerts; E.Rios Velazquez; R.T.H. Leijenaar; C. Parmar; P. Grossmann; S. Carvalho; J. Bussink; R. Monshouwer; B. Haibe-Kains; D. Rietveld; F. Hoebers; M.M. Rietbergen; R. Leemans; A. Dekker; J. Quackenbush; R.J. Gillies; P. Lambin | 2014 | 10.1038/ncomms5006 |
PET-based dose painting in non-small cell lung cancer: Comparing uniform dose escalation with boosting hypoxic and metabolically active sub-volumes. | A.J.G. Even; J. van der Stoep; C.M.L. Zegers; B. Reymen; E.G.C. Troost; P. Lambin; W. van Elmpt | 2015 | 10.1016/j.radonc.2015.07.013 |
Data from: A validated Tumor Control Probability model based on a meta-analysis of low, intermediate, and high-risk prostate cancer patients treated by photon, proton, or carbon-ion radiotherapy | S. Walsh; E. Roelofs; P. Kuess; P. Lambin; B. Jones; D. Georg; F. Verhaegen | 2015 | 10.17195/candat.2015.10.8 |